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1yo7
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1yo7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yo7, resolution 2.8Å" /> '''Re-engineering topolo...) |
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| - | [[Image:1yo7.gif|left|200px]]<br /><applet load="1yo7" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1yo7, resolution 2.8Å" /> | ||
| - | '''Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle'''<br /> | ||
| - | == | + | ==Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle== |
| - | + | <StructureSection load='1yo7' size='340' side='right'caption='[[1yo7]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1yo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YO7 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo7 OCA], [https://pdbe.org/1yo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yo7 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events. |
| - | [ | + | |
| - | + | ==See Also== | |
| + | *[[Rop protein|Rop protein]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Emery SC]] | ||
| + | [[Category: Sagermann M]] | ||
| + | [[Category: Sander C]] | ||
Current revision
Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle
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