2v31

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{{Seed}}
 
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[[Image:2v31.png|left|200px]]
 
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==Structure of First Catalytic Cysteine Half-domain of mouse ubiquitin- activating enzyme==
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The line below this paragraph, containing "STRUCTURE_2v31", creates the "Structure Box" on the page.
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<StructureSection load='2v31' size='340' side='right'caption='[[2v31]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2v31]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V31 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2V31 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z7l|1z7l]]</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2v31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v31 OCA], [http://pdbe.org/2v31 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v31 RCSB], [http://www.ebi.ac.uk/pdbsum/2v31 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v31 ProSAT]</span></td></tr>
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{{STRUCTURE_2v31| PDB=2v31 | SCENE= }}
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/UBA1_MOUSE UBA1_MOUSE]] Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/2v31_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v31 ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF FIRST CATALYTIC CYSTEINE HALF-DOMAIN OF MOUSE UBIQUITIN-ACTIVATING ENZYME===
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==See Also==
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*[[Ubiquitin activating enzyme|Ubiquitin activating enzyme]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2V31 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V31 OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:16738783</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bochtler, M.]]
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[[Category: Bochtler, M]]
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[[Category: Filipek, R.]]
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[[Category: Filipek, R]]
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[[Category: Jaremko, L.]]
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[[Category: Jaremko, L]]
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[[Category: Jaremko, M.]]
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[[Category: Jaremko, M]]
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[[Category: Szczepanowski, R H.]]
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[[Category: Szczepanowski, R H]]
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[[Category: Wojciechowski, W.]]
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[[Category: Wojciechowski, W]]
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[[Category: Zhukov, I.]]
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[[Category: Zhukov, I]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Catalytic domain]]
[[Category: Catalytic domain]]
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[[Category: Ubiquitination]]
[[Category: Ubiquitination]]
[[Category: Ubl conjugation pathway]]
[[Category: Ubl conjugation pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:46:24 2009''
 

Current revision

Structure of First Catalytic Cysteine Half-domain of mouse ubiquitin- activating enzyme

PDB ID 2v31

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