2fq3
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2fq3.png|left|200px]] | ||
| - | + | ==Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes== | |
| - | + | <StructureSection load='2fq3' size='340' side='right'caption='[[2fq3]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2fq3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQ3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fq3 OCA], [https://pdbe.org/2fq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2fq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fq3 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/SWI3_YEAST SWI3_YEAST] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | < | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fq/2fq3_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fq3 ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | __TOC__ | |
| - | == | + | </StructureSection> |
| - | < | + | [[Category: Large Structures]] |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Cairns | + | [[Category: Cairns BR]] |
| - | [[Category: Da | + | [[Category: Da G]] |
| - | [[Category: Lenkart | + | [[Category: Lenkart J]] |
| - | [[Category: Marmorstein | + | [[Category: Marmorstein R]] |
| - | [[Category: Shiekhattar | + | [[Category: Shiekhattar R]] |
| - | [[Category: Zhao | + | [[Category: Zhao K]] |
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Current revision
Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes
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