2zah

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{{Seed}}
 
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[[Image:2zah.png|left|200px]]
 
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==X-ray structure of Melon necrotic spot virus==
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The line below this paragraph, containing "STRUCTURE_2zah", creates the "Structure Box" on the page.
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<StructureSection load='2zah' size='340' side='right'caption='[[2zah]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2zah]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Melon_necrotic_spot_virus Melon necrotic spot virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZAH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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{{STRUCTURE_2zah| PDB=2zah | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zah OCA], [https://pdbe.org/2zah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zah RCSB], [https://www.ebi.ac.uk/pdbsum/2zah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zah ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_MNSV CAPSD_MNSV] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/2zah_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zah ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of melon necrotic spot virus (MNSV) was determined at 2.8 A resolution. Although MNSV is classified into the genus Carmovirus of the family Tombusviridae, the three-dimensional structure of MNSV showed a higher degree of similarity to tomato bushy stunt virus (TBSV), which belongs to the genus Tombusvirus, than to carnation mottle virus (CMtV), turnip crinkle virus (TCV) or cowpea mottle virus (CPMtV) from the genus Carmovirus. Thus, the classification of the family Tombusviridae at the genus level conflicts with the patterns of similarity among coat-protein structures. MNSV is one of the viruses belonging to the genera Tombusvirus or Carmovirus that are naturally transmitted in the soil by zoospores of fungal vectors. The X-ray structure of MNSV provides us with a representative structure of viruses transmitted by fungi.
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===X-ray structure of Melon necrotic spot virus===
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The structure of melon necrotic spot virus determined at 2.8 A resolution.,Wada Y, Tanaka H, Yamashita E, Kubo C, Ichiki-Uehara T, Nakazono-Nagaoka E, Omura T, Tsukihara T Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jan 1;64(Pt, 1):8-13. Epub 2007 Dec 20. PMID:18097092<ref>PMID:18097092</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18097092}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2zah" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18097092 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_18097092}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2ZAH is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Melon_necrotic_spot_virus Melon necrotic spot virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAH OCA].
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==Reference==
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<ref group="xtra">PMID:18097092</ref><references group="xtra"/>
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[[Category: Melon necrotic spot virus]]
[[Category: Melon necrotic spot virus]]
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[[Category: Omura, T.]]
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[[Category: Omura T]]
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[[Category: Tsukihara, T.]]
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[[Category: Tsukihara T]]
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[[Category: Wada, Y.]]
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[[Category: Wada Y]]
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[[Category: B-annulus]]
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[[Category: Capsid protein]]
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[[Category: Carmovirus]]
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[[Category: Coat protein]]
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[[Category: Fungal vector]]
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[[Category: Icosahedral virus]]
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[[Category: Mnsv]]
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[[Category: Plant virus]]
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[[Category: Tombusvirus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:32:22 2009''
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Current revision

X-ray structure of Melon necrotic spot virus

PDB ID 2zah

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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