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1z9a

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{{Seed}}
 
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[[Image:1z9a.png|left|200px]]
 
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<!--
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==Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+==
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The line below this paragraph, containing "STRUCTURE_1z9a", creates the "Structure Box" on the page.
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<StructureSection load='1z9a' size='340' side='right'caption='[[1z9a]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1z9a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Yamadazyma_tenuis Yamadazyma tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z9A FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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{{STRUCTURE_1z9a| PDB=1z9a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z9a OCA], [https://pdbe.org/1z9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z9a RCSB], [https://www.ebi.ac.uk/pdbsum/1z9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z9a ProSAT]</span></td></tr>
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</table>
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===Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+===
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== Function ==
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[https://www.uniprot.org/uniprot/XYL1_CANTE XYL1_CANTE] Reduces D-xylose into xylitol. Has a preference for NADPH, but can also utilize NADH as cosubstrate.
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16336198}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16336198 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z9/1z9a_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16336198}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Z9A is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Candida_tenuis Candida tenuis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z9A OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z9a ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:16336198</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Candida tenuis]]
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[[Category: Large Structures]]
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[[Category: Kratzer, R.]]
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[[Category: Yamadazyma tenuis]]
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[[Category: Leitgeb, S.]]
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[[Category: Kratzer R]]
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[[Category: Nidetzky, B.]]
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[[Category: Leitgeb S]]
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[[Category: Wilson, D K.]]
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[[Category: Nidetzky B]]
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[[Category: Akr]]
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[[Category: Wilson DK]]
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[[Category: Aldo-keto reductase]]
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[[Category: Beta-alpha-barrel]]
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[[Category: Candida tenui]]
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[[Category: Ketone reduction]]
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[[Category: Structure-activity correlation]]
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[[Category: Substrate selectivity]]
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[[Category: Xylose reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:40:00 2009''
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Current revision

Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+

PDB ID 1z9a

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