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1r4y

From Proteopedia

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{{Seed}}
 
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[[Image:1r4y.png|left|200px]]
 
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==SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN==
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The line below this paragraph, containing "STRUCTURE_1r4y", creates the "Structure Box" on the page.
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<StructureSection load='1r4y' size='340' side='right'caption='[[1r4y]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1r4y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_giganteus Aspergillus giganteus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R4Y FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4y OCA], [https://pdbe.org/1r4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r4y RCSB], [https://www.ebi.ac.uk/pdbsum/1r4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r4y ProSAT]</span></td></tr>
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{{STRUCTURE_1r4y| PDB=1r4y | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNAS_ASPGI RNAS_ASPGI] Alpha-sarcin is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bond in the 60S subunit of ribosomes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/1r4y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r4y ConSurf].
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<div style="clear:both"></div>
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===SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15044731}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15044731 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15044731}}
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==About this Structure==
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1R4Y is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Aspergillus_giganteus Aspergillus giganteus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4Y OCA].
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==Reference==
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<ref group="xtra">PMID:15044731</ref><references group="xtra"/>
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[[Category: Aspergillus giganteus]]
[[Category: Aspergillus giganteus]]
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[[Category: RRNA endonuclease]]
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[[Category: Large Structures]]
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[[Category: Bruix, M.]]
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[[Category: Bruix M]]
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[[Category: Garcia-Mayoral, M F.]]
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[[Category: Garcia-Mayoral MF]]
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[[Category: Garcia-Ortega, L.]]
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[[Category: Garcia-Ortega L]]
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[[Category: Gavilanes, J G.]]
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[[Category: Gavilanes JG]]
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[[Category: Lillo, M P.]]
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[[Category: Lillo MP]]
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[[Category: Pozo, A Martinez Del.]]
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[[Category: Martinez Del Pozo A]]
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[[Category: Rico, M.]]
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[[Category: Rico M]]
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[[Category: Santoro, J.]]
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[[Category: Santoro J]]
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[[Category: Alpha-beta protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:59:33 2009''
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Current revision

SOLUTION STRUCTURE OF THE DELETION MUTANT DELTA(7-22) OF THE CYTOTOXIC RIBONUCLEASE ALPHA-SARCIN

PDB ID 1r4y

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