2fwv

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{{Seed}}
 
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[[Image:2fwv.png|left|200px]]
 
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==Crystal Structure of Rv0813==
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The line below this paragraph, containing "STRUCTURE_2fwv", creates the "Structure Box" on the page.
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<StructureSection load='2fwv' size='340' side='right'caption='[[2fwv]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fwv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FWV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_2fwv| PDB=2fwv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwv OCA], [https://pdbe.org/2fwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fwv RCSB], [https://www.ebi.ac.uk/pdbsum/2fwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwv ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Rv0813===
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== Function ==
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[https://www.uniprot.org/uniprot/NB2_MYCTU NB2_MYCTU] Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.[HAMAP-Rule:MF_01297]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_17172346}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 17172346 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwv_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_17172346}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2FWV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWV OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fwv ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:17172346</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Large Structures]]
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[[Category: Alzari, P M.]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Betton, J M.]]
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[[Category: Alzari PM]]
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[[Category: Buschiazzo, A.]]
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[[Category: Betton JM]]
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[[Category: Cole, S T.]]
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[[Category: Buschiazzo A]]
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[[Category: Grana, M.]]
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[[Category: Cole ST]]
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[[Category: Haouz, A.]]
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[[Category: Grana M]]
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[[Category: SPINE, Structural Proteomics in Europe.]]
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[[Category: Haouz A]]
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[[Category: Shepard, W.]]
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[[Category: Shepard W]]
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[[Category: Conserved hypothetical]]
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[[Category: Fatty acid binding protein like]]
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[[Category: Restricted to actinomycete]]
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[[Category: Spine]]
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[[Category: Structural genomic]]
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[[Category: Structural proteomics in europe]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:00:05 2009''
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Current revision

Crystal Structure of Rv0813

PDB ID 2fwv

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