1rxj
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1rxj.png|left|200px]] | ||
| - | < | + | ==Crystal structure of streptavidin mutant (M2) where the L3,4 loop was replace by that of avidin== |
| - | + | <StructureSection load='1rxj' size='340' side='right'caption='[[1rxj]], [[Resolution|resolution]] 1.14Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1rxj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNI:5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC+ACID+(4-NITRO-PHENYL)-AMIDE'>BNI</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxj OCA], [https://pdbe.org/1rxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxj RCSB], [https://www.ebi.ac.uk/pdbsum/1rxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxj ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxj_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rxj ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Avidin 3D structures|Avidin 3D structures]] | |
| - | + | __TOC__ | |
| - | < | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
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[[Category: Streptomyces avidinii]] | [[Category: Streptomyces avidinii]] | ||
| - | [[Category: Bayer | + | [[Category: Bayer EA]] |
| - | [[Category: Eisenberg-Domovich | + | [[Category: Eisenberg-Domovich Y]] |
| - | [[Category: Livnah | + | [[Category: Livnah O]] |
| - | [[Category: Nir | + | [[Category: Nir O]] |
| - | [[Category: Pazy | + | [[Category: Pazy Y]] |
| - | [[Category: Raboy | + | [[Category: Raboy B]] |
| - | [[Category: Wilchek | + | [[Category: Wilchek M]] |
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Current revision
Crystal structure of streptavidin mutant (M2) where the L3,4 loop was replace by that of avidin
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