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3e66

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{{Seed}}
 
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[[Image:3e66.png|left|200px]]
 
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<!--
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==Crystal structure of the beta-finger domain of yeast Prp8==
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The line below this paragraph, containing "STRUCTURE_3e66", creates the "Structure Box" on the page.
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<StructureSection load='3e66' size='340' side='right'caption='[[3e66]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3e66]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E66 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e66 OCA], [https://pdbe.org/3e66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e66 RCSB], [https://www.ebi.ac.uk/pdbsum/3e66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e66 ProSAT]</span></td></tr>
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{{STRUCTURE_3e66| PDB=3e66 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/3e66_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3e66 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the beta-finger domain of yeast Prp8===
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==See Also==
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*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_18779563}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 18779563 is the PubMed ID number.
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</StructureSection>
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-->
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_18779563}}
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==About this Structure==
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3E66 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E66 OCA].
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==Reference==
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<ref group="xtra">PMID:18779563</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Heroux, A.]]
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[[Category: Heroux A]]
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[[Category: Xu, T.]]
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[[Category: Xu T]]
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[[Category: Yang, K.]]
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[[Category: Yang K]]
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[[Category: Zhang, L.]]
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[[Category: Zhang L]]
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[[Category: Zhao, R.]]
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[[Category: Zhao R]]
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[[Category: Beta-finger]]
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[[Category: Mrna processing]]
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[[Category: Mrna splicing]]
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[[Category: Nucleus]]
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[[Category: Rna-binding protein]]
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[[Category: Rnase h fold]]
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[[Category: Spliceosomal protein]]
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[[Category: Spliceosome]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:42:02 2009''
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Current revision

Crystal structure of the beta-finger domain of yeast Prp8

PDB ID 3e66

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