2owi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:04, 1 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2owi.png|left|200px]]
 
-
<!--
+
==Solution structure of the RGS domain from human RGS18==
-
The line below this paragraph, containing "STRUCTURE_2owi", creates the "Structure Box" on the page.
+
<StructureSection load='2owi' size='340' side='right'caption='[[2owi]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2owi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2h33 2h33]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OWI FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2owi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2owi OCA], [https://pdbe.org/2owi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2owi RCSB], [https://www.ebi.ac.uk/pdbsum/2owi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2owi ProSAT]</span></td></tr>
-
{{STRUCTURE_2owi| PDB=2owi | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RGS18_HUMAN RGS18_HUMAN] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.<ref>PMID:11042171</ref> <ref>PMID:11955952</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ow/2owi_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2owi ConSurf].
 +
<div style="clear:both"></div>
-
===Solution structure of the RGS domain from human RGS18===
+
==See Also==
-
 
+
*[[Regulator of G-protein signaling 3D structures|Regulator of G-protein signaling 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_18434541}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 18434541 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_18434541}}
+
-
 
+
-
==About this Structure==
+
-
2OWI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OWI OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:18434541</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Large Structures]]
-
[[Category: Ball, L J.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Bray, J.]]
+
[[Category: Ball LJ]]
-
[[Category: Brockmann, C.]]
+
[[Category: Bray J]]
-
[[Category: Diehl, A.]]
+
[[Category: Brockmann C]]
-
[[Category: Doyle, D A.]]
+
[[Category: Diehl A]]
-
[[Category: Edwards, A.]]
+
[[Category: Doyle DA]]
-
[[Category: Elkins, J.]]
+
[[Category: Edwards A]]
-
[[Category: Gileadi, C.]]
+
[[Category: Elkins J]]
-
[[Category: Higman, V A.]]
+
[[Category: Gileadi C]]
-
[[Category: Leidert, M.]]
+
[[Category: Higman VA]]
-
[[Category: Oschkinat, H.]]
+
[[Category: Leidert M]]
-
[[Category: Phillips, C.]]
+
[[Category: Oschkinat H]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Phillips C]]
-
[[Category: Schmieder, P.]]
+
[[Category: Schmieder P]]
-
[[Category: Schoch, G.]]
+
[[Category: Schoch G]]
-
[[Category: Soundararajan, M.]]
+
[[Category: Soundararajan M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Sundstrom M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Yang, X.]]
+
[[Category: Yang X]]
-
[[Category: Sgc]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:50:01 2009''
+

Current revision

Solution structure of the RGS domain from human RGS18

PDB ID 2owi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2owi"
Personal tools