This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1y17

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:59, 15 May 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1y17.png|left|200px]]
 
-
<!--
+
==crystal structure of Aa-X-bp-II, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus==
-
The line below this paragraph, containing "STRUCTURE_1y17", creates the "Structure Box" on the page.
+
<StructureSection load='1y17' size='340' side='right'caption='[[1y17]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1y17]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y17 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
{{STRUCTURE_1y17| PDB=1y17 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y17 OCA], [https://pdbe.org/1y17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y17 RCSB], [https://www.ebi.ac.uk/pdbsum/1y17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y17 ProSAT]</span></td></tr>
-
 
+
</table>
-
===crystal structure of Aa-X-bp-II, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/SLAA_DEIAC SLAA_DEIAC] Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX and factor X in the presence of calcium with a 1 to 1 stoichiometry. Also inhibits platelet aggregation by binding to platelet glycoprotein Ibalpha (GP1BA) and functioning as a blocker of vWF. Is devoid of hemorrhagic and lethal activities. Possess antithrombotic and thrombolytic activities. Also hydrolyzes the Aalpha-chain of fibrinogen. Does not affect the Bbeta-chain and the gamma chain (By similarity).
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
1Y17 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y17 OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y1/1y17_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y17 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Deinagkistrodon acutus]]
[[Category: Deinagkistrodon acutus]]
-
[[Category: Liang, Z.]]
+
[[Category: Large Structures]]
-
[[Category: Liu, S.]]
+
[[Category: Liang Z]]
-
[[Category: Mo, X.]]
+
[[Category: Liu S]]
-
[[Category: Niu, L.]]
+
[[Category: Mo X]]
-
[[Category: Teng, M.]]
+
[[Category: Niu L]]
-
[[Category: Yu, X.]]
+
[[Category: Teng M]]
-
[[Category: Zang, J.]]
+
[[Category: Yu X]]
-
[[Category: Zhao, W.]]
+
[[Category: Zang J]]
-
[[Category: Zhu, Z.]]
+
[[Category: Zhao W]]
-
[[Category: Aa-x-bp-ii]]
+
[[Category: Zhu Z]]
-
[[Category: Agkistrodon acutus]]
+
-
[[Category: C-type lectin-like protein]]
+
-
[[Category: Snake venom]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:06:19 2009''
+

Current revision

crystal structure of Aa-X-bp-II, a snake venom protein with the activity of binding to coagulation factor X from Agkistrodon acutus

PDB ID 1y17

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1y17"
Personal tools