1b1x

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{{Seed}}
 
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[[Image:1b1x.png|left|200px]]
 
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==STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION==
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The line below this paragraph, containing "STRUCTURE_1b1x", creates the "Structure Box" on the page.
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<StructureSection load='1b1x' size='340' side='right'caption='[[1b1x]], [[Resolution|resolution]] 2.62&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1b1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bgr 1bgr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B1X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.62&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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{{STRUCTURE_1b1x| PDB=1b1x | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b1x OCA], [https://pdbe.org/1b1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b1x RCSB], [https://www.ebi.ac.uk/pdbsum/1b1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b1x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRFL_HORSE TRFL_HORSE] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b1/1b1x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b1x ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION===
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==See Also==
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*[[Lactoferrin|Lactoferrin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10366507}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10366507 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10366507}}
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==About this Structure==
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1B1X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bgr 1bgr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B1X OCA].
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==Reference==
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<ref group="xtra">PMID:10366507</ref><references group="xtra"/>
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[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: Sharma, A K.]]
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[[Category: Large Structures]]
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[[Category: Singh, T P.]]
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[[Category: Sharma AK]]
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[[Category: Srinivasan, A.]]
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[[Category: Singh TP]]
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[[Category: Antibacterial]]
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[[Category: Srinivasan A]]
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[[Category: Iron binding protein]]
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[[Category: Lactoferrin]]
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[[Category: Structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:25:38 2009''
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Current revision

STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION

PDB ID 1b1x

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