1p35

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{{Seed}}
 
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[[Image:1p35.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF BACULOVIRUS P35==
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The line below this paragraph, containing "STRUCTURE_1p35", creates the "Structure Box" on the page.
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<StructureSection load='1p35' size='340' side='right'caption='[[1p35]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p35]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Autographa_californica_nucleopolyhedrovirus Autographa californica nucleopolyhedrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P35 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_1p35| PDB=1p35 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p35 OCA], [https://pdbe.org/1p35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p35 RCSB], [https://www.ebi.ac.uk/pdbsum/1p35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p35 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF BACULOVIRUS P35===
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== Function ==
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[https://www.uniprot.org/uniprot/P35_NPVAC P35_NPVAC] Functions as an inhibitor of the host RNA interference antiviral response. Inhibits the insect host cell apoptotic response initiated by the viral infection. Blocks as well the activity of members of the caspase family of proteases. Required for late and very late gene expression.<ref>PMID:16081248</ref> <ref>PMID:1962198</ref> <ref>PMID:26018163</ref>
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== Evolutionary Conservation ==
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10205157 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/1p35_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10205157}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1P35 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Autographa_californica_nucleopolyhedrovirus Autographa californica nucleopolyhedrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P35 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p35 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:10205157</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Autographa californica nucleopolyhedrovirus]]
[[Category: Autographa californica nucleopolyhedrovirus]]
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[[Category: Delacruz, W P.]]
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[[Category: Large Structures]]
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[[Category: Fisher, A J.]]
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[[Category: Delacruz WP]]
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[[Category: Friesen, P D.]]
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[[Category: Fisher AJ]]
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[[Category: Schneider, C L.]]
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[[Category: Friesen PD]]
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[[Category: Zoog, S J.]]
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[[Category: Schneider CL]]
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[[Category: Apoptosis]]
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[[Category: Zoog SJ]]
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[[Category: Baculovirus]]
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[[Category: Cell death]]
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[[Category: P35]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:33:55 2009''
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Current revision

CRYSTAL STRUCTURE OF BACULOVIRUS P35

PDB ID 1p35

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