2ec7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:39, 1 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ec7.png|left|200px]]
 
-
<!--
+
==Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein==
-
The line below this paragraph, containing "STRUCTURE_2ec7", creates the "Structure Box" on the page.
+
<StructureSection load='2ec7' size='340' side='right'caption='[[2ec7]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ec7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_2_(ISOLATE_GHANA-1) Human immunodeficiency virus type 2 (ISOLATE GHANA-1)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EC7 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_2ec7| PDB=2ec7 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ec7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ec7 OCA], [https://pdbe.org/2ec7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ec7 RCSB], [https://www.ebi.ac.uk/pdbsum/2ec7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ec7 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GAG_HV2G1 GAG_HV2G1] Matrix protein p17 targets Gag and Gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal. Also mediates nuclear localization of the preintegration complex (By similarity). Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity). p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ec7_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ec7 ConSurf].
 +
<div style="clear:both"></div>
-
===Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein===
+
==See Also==
-
 
+
*[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2EC7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_2 Human immunodeficiency virus 2]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC7 OCA].
+
[[Category: Large Structures]]
-
[[Category: Human immunodeficiency virus 2]]
+
[[Category: Endoh H]]
-
[[Category: Endoh, H.]]
+
[[Category: Kodera Y]]
-
[[Category: Kodera, Y.]]
+
[[Category: Kohno T]]
-
[[Category: Kohno, T.]]
+
[[Category: Komatsu H]]
-
[[Category: Komatsu, H.]]
+
[[Category: Maeda T]]
-
[[Category: Maeda, T.]]
+
[[Category: Matsui T]]
-
[[Category: Matsui, T.]]
+
[[Category: Miyauchi E]]
-
[[Category: Miyauchi, E.]]
+
[[Category: Tanaka H]]
-
[[Category: Tanaka, H.]]
+
[[Category: Tanaka T]]
-
[[Category: Tanaka, T.]]
+
-
[[Category: Hiv-2]]
+
-
[[Category: Nucleocapsid protein]]
+
-
[[Category: Rna recognition]]
+
-
[[Category: Viral protein]]
+
-
[[Category: Zinc finger]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:04:54 2009''
+

Current revision

Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein

PDB ID 2ec7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ec7"
Personal tools