1vzv

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{{Seed}}
 
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[[Image:1vzv.png|left|200px]]
 
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==STRUCTURE OF VARICELLA-ZOSTER VIRUS PROTEASE==
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The line below this paragraph, containing "STRUCTURE_1vzv", creates the "Structure Box" on the page.
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<StructureSection load='1vzv' size='340' side='right'caption='[[1vzv]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1vzv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_3 Human alphaherpesvirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VZV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vzv OCA], [https://pdbe.org/1vzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vzv RCSB], [https://www.ebi.ac.uk/pdbsum/1vzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vzv ProSAT]</span></td></tr>
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{{STRUCTURE_1vzv| PDB=1vzv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SCAF_VZVD SCAF_VZVD] Capsid scaffolding protein acts as a scaffold protein by binding major capsid protein 40 in the cytoplasm, inducing the nuclear localization of both proteins. Multimerizes in the nucleus such as protein 40 forms the icosahedral T=16 capsid. Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein 40. Cleavages products are evicted from the capsid before or during DNA packaging (By similarity). Assemblin is a protease essential for virion assembly in the nucleus. Catalyzes the cleavage of the assembly protein after complete capsid formation. Assemblin and cleavages products are evicted from the capsid before or during DNA packaging (By similarity). Assembly protein plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein 40. Multimerizes in the nucleus such as protein 40 forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/1vzv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vzv ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF VARICELLA-ZOSTER VIRUS PROTEASE===
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==See Also==
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*[[Virus protease 3D structures|Virus protease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9096314}}, adds the Publication Abstract to the page
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[[Category: Human alphaherpesvirus 3]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9096314 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Abdel-Meguid SS]]
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{{ABSTRACT_PUBMED_9096314}}
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[[Category: Culp JS]]
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[[Category: Debouck C]]
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==About this Structure==
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[[Category: Jason CA]]
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1VZV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Varicella-zoster_virus_(isolate_40a2) Varicella-zoster virus (isolate 40a2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VZV OCA].
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[[Category: Qiu X]]
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[[Category: Richardson SB]]
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==Reference==
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[[Category: Smith WW]]
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<ref group="xtra">PMID:9096314</ref><references group="xtra"/>
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[[Category: Abdel-Meguid, S S.]]
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[[Category: Culp, J S.]]
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[[Category: Debouck, C.]]
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[[Category: Jason, C A.]]
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[[Category: Qiu, X.]]
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[[Category: Richardson, S B.]]
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[[Category: Smith, W W.]]
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[[Category: Coat protein]]
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[[Category: Hydrolase]]
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[[Category: Serine protease]]
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[[Category: Varicella-zoster virus]]
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[[Category: Viral protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:20:00 2009''
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Current revision

STRUCTURE OF VARICELLA-ZOSTER VIRUS PROTEASE

PDB ID 1vzv

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