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2j66

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{{Seed}}
 
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[[Image:2j66.png|left|200px]]
 
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==Structural characterisation of BtrK decarboxylase from butirosin biosynthesis==
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The line below this paragraph, containing "STRUCTURE_2j66", creates the "Structure Box" on the page.
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<StructureSection load='2j66' size='340' side='right'caption='[[2j66]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2j66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Niallia_circulans Niallia circulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J66 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_2j66| PDB=2j66 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j66 OCA], [https://pdbe.org/2j66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j66 RCSB], [https://www.ebi.ac.uk/pdbsum/2j66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j66 ProSAT]</span></td></tr>
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</table>
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===STRUCTURAL CHARACTERISATION OF BTRK DECARBOXYLASE FROM BUTIROSIN BIOSYNTHESIS===
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== Function ==
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[https://www.uniprot.org/uniprot/BTRK_NIACI BTRK_NIACI] Pyridoxal phosphate-dependent decarboxylase that catalyzes 1 step in the biosynthesis of the side chain of the aminoglycoside antibiotics in the biosynthetic pathway of butirosin. Able to decarboxylate L-ornithine, L-arginine, L-lysine, but not L-glutamate or any D-amino acids. Has low activity with substrates not bound to an acyl-carrier protein.<ref>PMID:15975512</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2J66 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J66 OCA].
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Check<jmol>
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[[Category: Bacillus circulans]]
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<jmolCheckbox>
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[[Category: Blundell, T L.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j6/2j66_consurf.spt"</scriptWhenChecked>
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[[Category: Chirgadze, D Y.]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Li, Y.]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Popovic, B.]]
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</jmolCheckbox>
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[[Category: Spencer, J B.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j66 ConSurf].
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[[Category: Ahba biosynthesis]]
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<div style="clear:both"></div>
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[[Category: Butirosin]]
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== References ==
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[[Category: Decarboxylase]]
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<references/>
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[[Category: Lyase]]
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__TOC__
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</StructureSection>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:39:30 2009''
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[[Category: Large Structures]]
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[[Category: Niallia circulans]]
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[[Category: Blundell TL]]
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[[Category: Chirgadze DY]]
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[[Category: Li Y]]
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[[Category: Popovic B]]
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[[Category: Spencer JB]]

Current revision

Structural characterisation of BtrK decarboxylase from butirosin biosynthesis

PDB ID 2j66

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