2eqa
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2eqa.png|left|200px]] | ||
| - | + | ==Crystal Structure of the hypothetical Sua5 protein from Sulfolobus tokodaii== | |
| - | + | <StructureSection load='2eqa' size='340' side='right'caption='[[2eqa]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2eqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii Sulfurisphaera tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EQA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eqa OCA], [https://pdbe.org/2eqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eqa RCSB], [https://www.ebi.ac.uk/pdbsum/2eqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eqa ProSAT], [https://www.topsan.org/Proteins/RSGI/2eqa TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/SUA5_SULTO SUA5_SULTO] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity). Probably catalyzes the conversion of L-threonine, bicarbonate/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of pyrophosphate. Shows ATP hydrolysis activity in vitro, producing AMP.<ref>PMID:22383337</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/2eqa_consurf.spt"</scriptWhenChecked> |
| - | < | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eqa ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [ | + | == References == |
| - | [[ | + | <references/> |
| - | [ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [ | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Sulfurisphaera tokodaii]] |
| - | [[Category: | + | [[Category: Agari Y]] |
| - | [[Category: | + | [[Category: Kuramitsu S]] |
| - | [[Category: | + | [[Category: Shinkai A]] |
| - | [[Category: | + | [[Category: Yokoyama S]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the hypothetical Sua5 protein from Sulfolobus tokodaii
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