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1hqv

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{{Seed}}
 
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[[Image:1hqv.png|left|200px]]
 
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<!--
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==STRUCTURE OF APOPTOSIS-LINKED PROTEIN ALG-2==
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The line below this paragraph, containing "STRUCTURE_1hqv", creates the "Structure Box" on the page.
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<StructureSection load='1hqv' size='340' side='right'caption='[[1hqv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hqv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1hqv| PDB=1hqv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hqv OCA], [https://pdbe.org/1hqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hqv RCSB], [https://www.ebi.ac.uk/pdbsum/1hqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hqv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDCD6_MOUSE PDCD6_MOUSE] Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101 (By similarity). May mediate Ca(2+)-regulated signals along the death pathway. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/1hqv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hqv ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF APOPTOSIS-LINKED PROTEIN ALG-2===
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==See Also==
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*[[Cell death protein 3D structures|Cell death protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11525164}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11525164 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11525164}}
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==About this Structure==
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1HQV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQV OCA].
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==Reference==
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<ref group="xtra">PMID:11525164</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Berchtold, M.]]
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[[Category: Berchtold M]]
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[[Category: Cygler, M.]]
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[[Category: Cygler M]]
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[[Category: Hansen, C.]]
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[[Category: Hansen C]]
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[[Category: Jia, J.]]
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[[Category: Jia J]]
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[[Category: Tarabykina, S.]]
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[[Category: Tarabykina S]]
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[[Category: Calcium binding protein]]
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[[Category: Penta-ef-hand protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:32:54 2009''
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Current revision

STRUCTURE OF APOPTOSIS-LINKED PROTEIN ALG-2

PDB ID 1hqv

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