2p4h

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{{Seed}}
 
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[[Image:2p4h.png|left|200px]]
 
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==Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.)==
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The line below this paragraph, containing "STRUCTURE_2p4h", creates the "Structure Box" on the page.
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<StructureSection load='2p4h' size='340' side='right'caption='[[2p4h]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p4h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P4H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p4h OCA], [https://pdbe.org/2p4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p4h RCSB], [https://www.ebi.ac.uk/pdbsum/2p4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p4h ProSAT]</span></td></tr>
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{{STRUCTURE_2p4h| PDB=2p4h | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.)===
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[https://www.uniprot.org/uniprot/VESTR_MEDSA VESTR_MEDSA] Stereospecific enzyme that catalyzes the NADPH-dependent reduction of (3R)-vestitone to (3R,4R)-4'-methoxyisoflavan-2',4,7-triol (DMI). Has no activity with (3S)-vestitone. Catalyzes the penultimate step in the biosynthesis of the phytoalexin medicarpin, and thereby contributes to plant defense reactions.<ref>PMID:7625843</ref> <ref>PMID:7805842</ref> <ref>PMID:8071365</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17433362 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/2p4h_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17433362}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p4h ConSurf].
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2P4H is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Medicago_sativa Medicago sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4H OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:17433362</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Medicago sativa]]
[[Category: Medicago sativa]]
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[[Category: Dixon, R A.]]
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[[Category: Dixon RA]]
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[[Category: Shao, H.]]
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[[Category: Shao H]]
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[[Category: Wang, X.]]
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[[Category: Wang X]]
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[[Category: Crystal structure]]
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[[Category: Isoflavonoid]]
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[[Category: Nadph-dependent reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:48:22 2009''
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Current revision

Crystal Structure of Vestitone Reductase from Alfalfa (Medicago sativa L.)

PDB ID 2p4h

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