1nn1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:57, 14 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1nn1.png|left|200px]]
 
-
<!--
+
==Crystal structure of human thymidylate kinase with ddTMP and AppNHp==
-
The line below this paragraph, containing "STRUCTURE_1nn1", creates the "Structure Box" on the page.
+
<StructureSection load='1nn1' size='340' side='right'caption='[[1nn1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1nn1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NN1 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DT:3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>2DT</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_1nn1| PDB=1nn1 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nn1 OCA], [https://pdbe.org/1nn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nn1 RCSB], [https://www.ebi.ac.uk/pdbsum/1nn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nn1 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KTHY_HUMAN KTHY_HUMAN] Catalyzes the conversion of dTMP to dTDP.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/1nn1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nn1 ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of human thymidylate kinase with ddTMP and AppNHp===
+
==See Also==
-
 
+
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_12614151}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 12614151 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_12614151}}
+
-
 
+
-
==About this Structure==
+
-
1NN1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NN1 OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:12614151</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: DTMP kinase]]
+
[[Category: Large Structures]]
-
[[Category: Konrad, M.]]
+
[[Category: Konrad M]]
-
[[Category: Lavie, A.]]
+
[[Category: Lavie A]]
-
[[Category: Meier, C.]]
+
[[Category: Meier C]]
-
[[Category: Monnerjahn, M.]]
+
[[Category: Monnerjahn M]]
-
[[Category: Ostermann, N.]]
+
[[Category: Ostermann N]]
-
[[Category: Segura-Pena, D.]]
+
[[Category: Segura-Pena D]]
-
[[Category: Veit, T.]]
+
[[Category: Veit T]]
-
[[Category: Dideoxythymidine]]
+
-
[[Category: P-loop]]
+
-
[[Category: Thymidylate kinase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:56:12 2009''
+

Current revision

Crystal structure of human thymidylate kinase with ddTMP and AppNHp

PDB ID 1nn1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nn1"
Personal tools