This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2a1y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2a1y" size="450" color="white" frame="true" align="right" spinBox="true" caption="2a1y, resolution 2.27&Aring;" /> '''Crystal Structure of...)
Current revision (07:17, 23 August 2023) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2a1y.gif|left|200px]]<br /><applet load="2a1y" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2a1y, resolution 2.27&Aring;" />
 
-
'''Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.'''<br />
 
-
==About this Structure==
+
==Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.==
-
2A1Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] with 5GP as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/GMP_reductase GMP reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.1.7 1.7.1.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2A1Y OCA].
+
<StructureSection load='2a1y' size='340' side='right'caption='[[2a1y]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2a1y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A1Y FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1y OCA], [https://pdbe.org/2a1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a1y RCSB], [https://www.ebi.ac.uk/pdbsum/2a1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a1y ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GUAC_BACAN GUAC_BACAN] Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a1y_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a1y ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
-
[[Category: GMP reductase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Blagova EV]]
-
[[Category: Blagova, E.V.]]
+
[[Category: Brannigan JA]]
-
[[Category: Brannigan, J.A.]]
+
[[Category: Fogg MJ]]
-
[[Category: Fogg, M.J.]]
+
[[Category: Grenha R]]
-
[[Category: Grenha, R.]]
+
[[Category: Levdikov VM]]
-
[[Category: Levdikov, V.M.]]
+
[[Category: Wilkinson AJ]]
-
[[Category: SPINE, Structural.Proteomics.in.Europe.]]
+
[[Category: Wilson KS]]
-
[[Category: Wilkinson, A.J.]]
+
-
[[Category: Wilson, K.S.]]
+
-
[[Category: 5GP]]
+
-
[[Category: and nucleotides: nucleotide and nucleoside interconversions]]
+
-
[[Category: gmp]]
+
-
[[Category: guac]]
+
-
[[Category: nucleosides]]
+
-
[[Category: purines]]
+
-
[[Category: pyrimidines]]
+
-
[[Category: spine]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural proteomics in europe]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 07:52:22 2007''
+

Current revision

Crystal Structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A Resolution.

PDB ID 2a1y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2a1y"
Personal tools