1jys

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{{Seed}}
 
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[[Image:1jys.png|left|200px]]
 
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==Crystal Structure of E. coli MTA/AdoHcy Nucleosidase==
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The line below this paragraph, containing "STRUCTURE_1jys", creates the "Structure Box" on the page.
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<StructureSection load='1jys' size='340' side='right'caption='[[1jys]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jys]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene></td></tr>
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{{STRUCTURE_1jys| PDB=1jys | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jys OCA], [https://pdbe.org/1jys PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jys RCSB], [https://www.ebi.ac.uk/pdbsum/1jys PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jys ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of E. coli MTA/AdoHcy Nucleosidase===
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== Function ==
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[https://www.uniprot.org/uniprot/MTNN_ECOLI MTNN_ECOLI] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates.[HAMAP-Rule:MF_01684]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11591349}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11591349 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jy/1jys_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11591349}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1JYS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYS OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jys ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:11591349</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Adenosylhomocysteine nucleosidase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Cornell, K A.]]
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[[Category: Large Structures]]
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[[Category: Howell, P L.]]
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[[Category: Cornell KA]]
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[[Category: Lee, J E.]]
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[[Category: Howell PL]]
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[[Category: Riscoe, M K.]]
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[[Category: Lee JE]]
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[[Category: Dimer]]
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[[Category: Riscoe MK]]
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[[Category: Mixed alpha/beta]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:27:30 2009''
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Current revision

Crystal Structure of E. coli MTA/AdoHcy Nucleosidase

PDB ID 1jys

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