1xfn

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{{Seed}}
 
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[[Image:1xfn.png|left|200px]]
 
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==NMR structure of the ground state of the photoactive yellow protein lacking the N-terminal part==
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The line below this paragraph, containing "STRUCTURE_1xfn", creates the "Structure Box" on the page.
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<StructureSection load='1xfn' size='340' side='right'caption='[[1xfn]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XFN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
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{{STRUCTURE_1xfn| PDB=1xfn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xfn OCA], [https://pdbe.org/1xfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xfn RCSB], [https://www.ebi.ac.uk/pdbsum/1xfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xfn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xf/1xfn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xfn ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The N-terminally truncated variant of photoactive yellow protein (Delta25-PYP) undergoes a very similar photocycle as the corresponding wild-type protein (WT-PYP), although the lifetime of its light-illuminated (pB) state is much longer. This has allowed determination of the structure of both its dark- (pG) as well as its pB-state in solution by nuclear magnetic resonance (NMR) spectroscopy. The pG structure shows a well-defined fold, similar to WT-PYP and the X-ray structure of the pG state of Delta25-PYP. In the long-lived photocycle intermediate pB, the central beta sheet is still intact, as well as a small part of one alpha helix. The remainder of pB is unfolded and highly flexible, as evidenced by results from proton-deuterium exchange and NMR relaxation studies. Thus, the partially unfolded nature of the presumed signaling state of PYP in solution, as suggested previously, has now been structurally demonstrated.
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===NMR structure of the ground state of the photoactive yellow protein lacking the N-terminal part===
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The solution structure of a transient photoreceptor intermediate: Delta25 photoactive yellow protein.,Bernard C, Houben K, Derix NM, Marks D, van der Horst MA, Hellingwerf KJ, Boelens R, Kaptein R, van Nuland NA Structure. 2005 Jul;13(7):953-62. PMID:16004868<ref>PMID:16004868</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_16004868}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1xfn" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 16004868 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_16004868}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1XFN is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XFN OCA].
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==Reference==
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<ref group="xtra">PMID:16004868</ref><references group="xtra"/>
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[[Category: Halorhodospira halophila]]
[[Category: Halorhodospira halophila]]
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[[Category: Bernard, C.]]
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[[Category: Large Structures]]
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[[Category: Boelens, R.]]
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[[Category: Bernard C]]
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[[Category: Derix, N M.]]
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[[Category: Boelens R]]
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[[Category: Hellingwerf, K J.]]
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[[Category: Derix NM]]
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[[Category: Horst, M A.van der.]]
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[[Category: Hellingwerf KJ]]
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[[Category: Houben, K.]]
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[[Category: Houben K]]
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[[Category: Kaptein, R.]]
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[[Category: Kaptein R]]
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[[Category: Marks, D.]]
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[[Category: Marks D]]
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[[Category: Nuland, N A.van.]]
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[[Category: Van Nuland NA]]
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[[Category: Pas domain]]
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[[Category: Van der Horst MA]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:10:03 2009''
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Current revision

NMR structure of the ground state of the photoactive yellow protein lacking the N-terminal part

PDB ID 1xfn

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