1xl6

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{{Seed}}
 
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[[Image:1xl6.png|left|200px]]
 
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==Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1==
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The line below this paragraph, containing "STRUCTURE_1xl6", creates the "Structure Box" on the page.
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<StructureSection load='1xl6' size='340' side='right'caption='[[1xl6]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1xl6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XL6 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
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{{STRUCTURE_1xl6| PDB=1xl6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl6 OCA], [https://pdbe.org/1xl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xl6 RCSB], [https://www.ebi.ac.uk/pdbsum/1xl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xl6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xl/1xl6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xl6 ConSurf].
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<div style="clear:both"></div>
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===Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1===
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==See Also==
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*[[Potassium channel 3D structures|Potassium channel 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1XL6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL6 OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Magnetospirillum magnetotacticum]]
[[Category: Magnetospirillum magnetotacticum]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Doyle, D A.]]
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[[Category: Doyle DA]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Gulbis, J M.]]
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[[Category: Gulbis JM]]
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[[Category: Kuo, A.]]
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[[Category: Kuo A]]
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[[Category: Smith, B.]]
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[[Category: Smith B]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom M]]
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[[Category: Integral membrane protein]]
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[[Category: Inwardly rectifying k+ channel]]
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[[Category: Ion channel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:30:46 2009''
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Current revision

Intermediate gating structure 2 of the inwardly rectifying K+ channel KirBac3.1

PDB ID 1xl6

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