2c7k

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{{Seed}}
 
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[[Image:2c7k.png|left|200px]]
 
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==Laue structure of phycoerythrocyanin from Mastigocladus laminosus==
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The line below this paragraph, containing "STRUCTURE_2c7k", creates the "Structure Box" on the page.
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<StructureSection load='2c7k' size='340' side='right'caption='[[2c7k]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2c7k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mastigocladus_laminosus Mastigocladus laminosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7K FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLA:BILIVERDINE+IX+ALPHA'>BLA</scene>, <scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene></td></tr>
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{{STRUCTURE_2c7k| PDB=2c7k | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7k OCA], [https://pdbe.org/2c7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7k RCSB], [https://www.ebi.ac.uk/pdbsum/2c7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7k ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHEA_MASLA PHEA_MASLA] Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7k ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Phycoerythrocyanin is the only cyanobacterial phycobiliprotein containing phycoviolobilin as a chromophore. The phycoviolobilin chromophore is photo-reactive; upon irradiation, the chromophore undergoes a Z/E-isomerization involving the rotation of pyrrole-ring D. We have determined the structure of trimeric phycoerythrocyanin at three different experimental settings: monochromatically at 110 K and 295 K as well as with the Laue method at 288 K. Based on their chemical structures, the restraints for the phycoviolobilin of the alpha-subunit and for the phycocyanobilin chromophores of the beta-subunit were newly generated, which allows a chemically meaningful refinement of both chromophores. All three phycoerythrocyanin structures are very similar; the subunits match within 0.5 A. The detailed comparison of the data obtained with the different measurements provided information about the protein properties around the phycoviolobilin chromophore. For the first time, crystals of a phycobilisome protein are used successfully with the Laue technique. This paves the way for time-resolved macromolecular crystallography, which is able to elucidate the exact mechanisms of the phycoviolobilin photoactivity including the protein involvement.
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===LAUE STRUCTURE OF PHYCOERYTHROCYANIN FROM MASTIGOCLADUS LAMINOSUS===
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Local protein flexibility as a prerequisite for reversible chromophore isomerization in alpha-phycoerythrocyanin.,Schmidt M, Krasselt A, Reuter W Biochim Biophys Acta. 2006 Jan;1764(1):55-62. Epub 2005 Nov 21. PMID:16377266<ref>PMID:16377266</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_16377266}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 2c7k" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 16377266 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_16377266}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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2C7K is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mastigocladus_laminosus Mastigocladus laminosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7K OCA].
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==Reference==
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<ref group="xtra">PMID:16377266</ref><references group="xtra"/>
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[[Category: Mastigocladus laminosus]]
[[Category: Mastigocladus laminosus]]
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[[Category: Krasselt, A.]]
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[[Category: Krasselt A]]
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[[Category: Reuter, W.]]
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[[Category: Reuter W]]
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[[Category: Schmidt, M.]]
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[[Category: Schmidt M]]
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[[Category: Antenna protein]]
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[[Category: Bile pigment]]
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[[Category: Chromophore]]
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[[Category: Electron transport]]
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[[Category: Photosynthesis]]
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[[Category: Phycobilisome]]
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[[Category: Phycocyanobilin]]
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[[Category: Phycoerythrocyanin]]
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[[Category: Phycoviolobilin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:59:02 2009''
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Current revision

Laue structure of phycoerythrocyanin from Mastigocladus laminosus

PDB ID 2c7k

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