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1ri8

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{{Seed}}
 
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[[Image:1ri8.png|left|200px]]
 
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==Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme==
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The line below this paragraph, containing "STRUCTURE_1ri8", creates the "Structure Box" on the page.
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<StructureSection load='1ri8' size='340' side='right'caption='[[1ri8]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ri8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RI8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1ri8| PDB=1ri8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ri8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ri8 OCA], [https://pdbe.org/1ri8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ri8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ri8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ri8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/1ri8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ri8 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme===
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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<!--
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15659390}}, adds the Publication Abstract to the page
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== References ==
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(as it appears on PubMed at http://www.pubmed.gov), where 15659390 is the PubMed ID number.
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<references/>
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__TOC__
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{{ABSTRACT_PUBMED_15659390}}
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</StructureSection>
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==About this Structure==
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1RI8 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RI8 OCA].
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==Reference==
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<ref group="xtra">PMID:15659390</ref><references group="xtra"/>
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[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Decanniere, K.]]
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[[Category: De Genst E]]
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[[Category: Genst, E De.]]
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[[Category: Decanniere K]]
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[[Category: Ghahroudi, M A.]]
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[[Category: Ghahroudi MA]]
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[[Category: Kinne, J.]]
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[[Category: Kinne J]]
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[[Category: Loris, R.]]
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[[Category: Loris R]]
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[[Category: Muyldermans, S.]]
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[[Category: Muyldermans S]]
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[[Category: Silence, K.]]
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[[Category: Silence K]]
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[[Category: Wyns, L.]]
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[[Category: Wyns L]]
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[[Category: Alpha-beta orthogonal bundle]]
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[[Category: Beta sandwich]]
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[[Category: Immunoglobulin fold]]
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[[Category: Vhh-lysozyme complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:39:39 2009''
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Current revision

Crystal Structure of the Camelid Single Domain Antibody 1D2L19 in complex with Hen Egg White Lysozyme

PDB ID 1ri8

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