2qv6

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{{Seed}}
 
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[[Image:2qv6.png|left|200px]]
 
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==GTP cyclohydrolase III from M. jannaschii (MJ0145) complexed with GTP and metal ions==
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The line below this paragraph, containing "STRUCTURE_2qv6", creates the "Structure Box" on the page.
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<StructureSection load='2qv6' size='340' side='right'caption='[[2qv6]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2qv6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QV6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_2qv6| PDB=2qv6 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qv6 OCA], [https://pdbe.org/2qv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qv6 RCSB], [https://www.ebi.ac.uk/pdbsum/2qv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qv6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GCH3_METJA GCH3_METJA] Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.[HAMAP-Rule:MF_00608]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qv6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qv6 ConSurf].
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<div style="clear:both"></div>
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===GTP cyclohydrolase III from M. jannaschii (MJ0145) complexed with GTP and metal ions===
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==See Also==
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*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18052207}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 18052207 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18052207}}
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==About this Structure==
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2QV6 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QV6 OCA].
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==Reference==
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<ref group="xtra">PMID:18052207</ref><references group="xtra"/>
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[[Category: GTP cyclohydrolase IIa]]
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[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: Bandarian, V.]]
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[[Category: Bandarian V]]
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[[Category: Roberts, S A.]]
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[[Category: Roberts SA]]
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[[Category: Enzyme]]
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[[Category: Fapy]]
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[[Category: Gtp]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:42:53 2009''
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Current revision

GTP cyclohydrolase III from M. jannaschii (MJ0145) complexed with GTP and metal ions

PDB ID 2qv6

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