1ycl

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{{Seed}}
 
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[[Image:1ycl.png|left|200px]]
 
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==Crystal Structure of B. subtilis LuxS in Complex with a Catalytic 2-Ketone Intermediate==
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The line below this paragraph, containing "STRUCTURE_1ycl", creates the "Structure Box" on the page.
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<StructureSection load='1ycl' size='340' side='right'caption='[[1ycl]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ycl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YCL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=KRI:(S)-2-AMINO-4-[(2S,3R)-2,3,5-TRIHYDROXY-4-OXO-PENTYL]MERCAPTO-BUTYRIC+ACID'>KRI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1ycl| PDB=1ycl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ycl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ycl OCA], [https://pdbe.org/1ycl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ycl RCSB], [https://www.ebi.ac.uk/pdbsum/1ycl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ycl ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of B. subtilis LuxS in Complex with a Catalytic 2-Ketone Intermediate===
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== Function ==
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[https://www.uniprot.org/uniprot/LUXS_BACSU LUXS_BACSU] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15751951}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15751951 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yc/1ycl_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15751951}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1YCL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YCL OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ycl ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:15751951</ref><references group="xtra"/>
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Bell, C E.]]
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[[Category: Large Structures]]
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[[Category: Hu, X.]]
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[[Category: Bell CE]]
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[[Category: Pei, D.]]
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[[Category: Hu X]]
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[[Category: Rajan, R.]]
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[[Category: Pei D]]
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[[Category: Zhu, J.]]
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[[Category: Rajan R]]
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[[Category: Metalloenzyme]]
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[[Category: Zhu J]]
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[[Category: Quorum sensing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:00:47 2009''
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Current revision

Crystal Structure of B. subtilis LuxS in Complex with a Catalytic 2-Ketone Intermediate

PDB ID 1ycl

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