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2av5

From Proteopedia

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{{Seed}}
 
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[[Image:2av5.png|left|200px]]
 
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<!--
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==Crystal structure of Pyrococcus furiosus Pop5, an archaeal Ribonuclease P protein==
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The line below this paragraph, containing "STRUCTURE_2av5", creates the "Structure Box" on the page.
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<StructureSection load='2av5' size='340' side='right'caption='[[2av5]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2av5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AV5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2av5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2av5 OCA], [https://pdbe.org/2av5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2av5 RCSB], [https://www.ebi.ac.uk/pdbsum/2av5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2av5 ProSAT]</span></td></tr>
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{{STRUCTURE_2av5| PDB=2av5 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNP2_PYRFU RNP2_PYRFU] Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. The RNA is catalytic, but its KM for pre-tRNA is 170-fold decreased in the presence of the 4 known protein subunits (Rnp1-4). The protein subunits also decrease the amount of Mg(2+) needed for activity.<ref>PMID:17053064</ref> <ref>PMID:21683084</ref> <ref>PMID:22298511</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/av/2av5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2av5 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of Pyrococcus furiosus Pop5, an archaeal Ribonuclease P protein===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_16418270}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 16418270 is the PubMed ID number.
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</StructureSection>
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-->
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_16418270}}
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==About this Structure==
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2AV5 is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AV5 OCA].
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==Reference==
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<ref group="xtra">PMID:16418270</ref><references group="xtra"/>
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Ribonuclease P]]
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[[Category: Bell CE]]
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[[Category: Bell, C E.]]
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[[Category: Bohlen CJ]]
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[[Category: Bohlen, C J.]]
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[[Category: Foster MP]]
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[[Category: Foster, M P.]]
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[[Category: Wilson RC]]
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[[Category: Wilson, R C.]]
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[[Category: Ribonuclease p]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:11:24 2009''
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Current revision

Crystal structure of Pyrococcus furiosus Pop5, an archaeal Ribonuclease P protein

PDB ID 2av5

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