1uxc

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{{Seed}}
 
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[[Image:1uxc.png|left|200px]]
 
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==FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE==
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The line below this paragraph, containing "STRUCTURE_1uxc", creates the "Structure Box" on the page.
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<StructureSection load='1uxc' size='340' side='right'caption='[[1uxc]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1uxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UXC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uxc OCA], [https://pdbe.org/1uxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uxc RCSB], [https://www.ebi.ac.uk/pdbsum/1uxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uxc ProSAT]</span></td></tr>
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{{STRUCTURE_1uxc| PDB=1uxc | SCENE= }}
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</table>
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== Function ==
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===FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE===
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[https://www.uniprot.org/uniprot/CRA_ECOLI CRA_ECOLI] Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator.<ref>PMID:16115199</ref> <ref>PMID:8195118</ref> <ref>PMID:8230205</ref> <ref>PMID:8550429</ref> <ref>PMID:8577250</ref> <ref>PMID:8858581</ref> <ref>PMID:9084760</ref> <ref>PMID:9371462</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_9237914}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 9237914 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ux/1uxc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_9237914}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uxc ConSurf].
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1UXC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UXC OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:9237914</ref><references group="xtra"/>
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Bockmann, A.]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bonod-Bidaud, C.]]
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[[Category: Large Structures]]
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[[Category: Cortay, J C.]]
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[[Category: Bockmann A]]
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[[Category: Cozzone, A J.]]
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[[Category: Bonod-Bidaud C]]
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[[Category: Deleage, G.]]
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[[Category: Cortay JC]]
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[[Category: Geourjon, C.]]
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[[Category: Cozzone AJ]]
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[[Category: Lesage, A.]]
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[[Category: Deleage G]]
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[[Category: Montserret, R.]]
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[[Category: Geourjon C]]
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[[Category: Negre, D.]]
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[[Category: Lesage A]]
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[[Category: Penin, F.]]
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[[Category: Montserret R]]
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[[Category: Yang, Y.]]
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[[Category: Negre D]]
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[[Category: Dna-binding protein]]
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[[Category: Penin F]]
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[[Category: Fructose repressor]]
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[[Category: Yang Y]]
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[[Category: Laci family]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:24:23 2009''
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Current revision

FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE

PDB ID 1uxc

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