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1qub

From Proteopedia

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{{Seed}}
 
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[[Image:1qub.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF THE GLYCOSYLATED FIVE-DOMAIN HUMAN BETA2-GLYCOPROTEIN I PURIFIED FROM BLOOD PLASMA==
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The line below this paragraph, containing "STRUCTURE_1qub", creates the "Structure Box" on the page.
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<StructureSection load='1qub' size='340' side='right'caption='[[1qub]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qub]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QUB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1qub| PDB=1qub | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qub OCA], [https://pdbe.org/1qub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qub RCSB], [https://www.ebi.ac.uk/pdbsum/1qub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qub ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF THE GLYCOSYLATED FIVE-DOMAIN HUMAN BETA2-GLYCOPROTEIN I PURIFIED FROM BLOOD PLASMA===
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== Function ==
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[https://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10508150}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10508150 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qu/1qub_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10508150}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1QUB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QUB OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qub ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:10508150</ref><references group="xtra"/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bouma, B.]]
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[[Category: Large Structures]]
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[[Category: Derksen, R H.W M.]]
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[[Category: Bouma B]]
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[[Category: Elsen, J M.H van den.]]
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[[Category: Derksen RHWM]]
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[[Category: Groot, Ph G.de.]]
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[[Category: Gros P]]
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[[Category: Gros, P.]]
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[[Category: Kroon J]]
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[[Category: Kroon, J.]]
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[[Category: Ravelli RBG]]
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[[Category: Ravelli, R B.G.]]
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[[Category: Schouten A]]
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[[Category: Schouten, A.]]
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[[Category: Simmelink MJA]]
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[[Category: Simmelink, M J.A.]]
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[[Category: De Groot PG]]
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[[Category: Complement control protein]]
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[[Category: Van den Elsen JMH]]
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[[Category: Membrane adhesion]]
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[[Category: Multi-domain]]
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[[Category: N-glycosylation]]
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[[Category: Short consensus repeat]]
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[[Category: Sushi]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:46:30 2009''
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Current revision

CRYSTAL STRUCTURE OF THE GLYCOSYLATED FIVE-DOMAIN HUMAN BETA2-GLYCOPROTEIN I PURIFIED FROM BLOOD PLASMA

PDB ID 1qub

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