1oy9

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{{Seed}}
 
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[[Image:1oy9.png|left|200px]]
 
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==Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump==
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The line below this paragraph, containing "STRUCTURE_1oy9", creates the "Structure Box" on the page.
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<StructureSection load='1oy9' size='340' side='right'caption='[[1oy9]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oy9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OY9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ET:ETHIDIUM'>ET</scene></td></tr>
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{{STRUCTURE_1oy9| PDB=1oy9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oy9 OCA], [https://pdbe.org/1oy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1oy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oy9 ProSAT]</span></td></tr>
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</table>
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===Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump===
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== Function ==
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[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12738864}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12738864 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oy/1oy9_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12738864}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1OY9 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OY9 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oy9 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:12738864</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Jr., D E.Koshland.]]
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[[Category: Large Structures]]
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[[Category: McDermott, G.]]
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[[Category: Koshland Jr DE]]
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[[Category: Nikaido, H.]]
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[[Category: McDermott G]]
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[[Category: Yu, E W.]]
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[[Category: Nikaido H]]
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[[Category: Zgurskaya, H I.]]
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[[Category: Yu EW]]
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[[Category: Membrane protein]]
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[[Category: Zgurskaya HI]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:25:56 2009''
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Current revision

Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump

PDB ID 1oy9

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