This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1fmb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:16, 7 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1fmb.png|left|200px]]
 
-
<!--
+
==EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793==
-
The line below this paragraph, containing "STRUCTURE_1fmb", creates the "Structure Box" on the page.
+
<StructureSection load='1fmb' size='340' side='right'caption='[[1fmb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1fmb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FMB FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYB:[2-(2-METHYL-PROPANE-2-SULFONYLMETHYL)-3-NAPHTHALEN-1-YL-PROPIONYL-VALINYL]-PHENYLALANINOL'>HYB</scene></td></tr>
-
{{STRUCTURE_1fmb| PDB=1fmb | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fmb OCA], [https://pdbe.org/1fmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fmb RCSB], [https://www.ebi.ac.uk/pdbsum/1fmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fmb ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/POL_EIAVC POL_EIAVC] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fm/1fmb_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fmb ConSurf].
 +
<div style="clear:both"></div>
-
===EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793===
+
==See Also==
-
 
+
*[[Virus protease 3D structures|Virus protease 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_8844837}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 8844837 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8844837}}
+
-
 
+
-
==About this Structure==
+
-
1FMB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Equine_infectious_anemia_virus Equine infectious anemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FMB OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:8844837</ref><references group="xtra"/>
+
[[Category: Equine infectious anemia virus]]
[[Category: Equine infectious anemia virus]]
-
[[Category: HIV-1 retropepsin]]
+
[[Category: Large Structures]]
-
[[Category: Gustchina, A.]]
+
[[Category: Gustchina A]]
-
[[Category: Kervinen, J.]]
+
[[Category: Kervinen J]]
-
[[Category: Wlodawer, A.]]
+
[[Category: Wlodawer A]]
-
[[Category: Zdanov, A.]]
+
[[Category: Zdanov A]]
-
[[Category: Aspartyl protease]]
+
-
[[Category: Endonuclease]]
+
-
[[Category: Polyprotein]]
+
-
[[Category: Rna-directed dna polymerase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:43:25 2009''
+

Current revision

EIAV PROTEASE COMPLEXED WITH THE INHIBITOR HBY-793

PDB ID 1fmb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fmb"
Personal tools