1g5v

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{{Seed}}
 
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[[Image:1g5v.png|left|200px]]
 
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<!--
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==SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN==
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The line below this paragraph, containing "STRUCTURE_1g5v", creates the "Structure Box" on the page.
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<StructureSection load='1g5v' size='340' side='right'caption='[[1g5v]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1g5v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G5V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g5v OCA], [https://pdbe.org/1g5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g5v RCSB], [https://www.ebi.ac.uk/pdbsum/1g5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g5v ProSAT]</span></td></tr>
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{{STRUCTURE_1g5v| PDB=1g5v | SCENE= }}
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</table>
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== Function ==
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===SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN===
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[https://www.uniprot.org/uniprot/SMN_HUMAN SMN_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11135666}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11135666 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g5/1g5v_consurf.spt"</scriptWhenChecked>
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-->
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11135666}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Disease==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g5v ConSurf].
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Known disease associated with this structure: Spinal muscular atrophy-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600354 600354]], Spinal muscular atrophy-2 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600354 600354]], Spinal muscular atrophy-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600354 600354]], Spinal muscular atrophy-4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600354 600354]]
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<div style="clear:both"></div>
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__TOC__
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==About this Structure==
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</StructureSection>
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1G5V is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5V OCA].
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==Reference==
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<ref group="xtra">PMID:11135666</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Buehler, D.]]
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[[Category: Large Structures]]
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[[Category: Fischer, U.]]
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[[Category: Buehler D]]
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[[Category: Sattler, M.]]
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[[Category: Fischer U]]
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[[Category: Selenko, P.]]
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[[Category: Sattler M]]
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[[Category: Sprangers, R.]]
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[[Category: Selenko P]]
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[[Category: Stier, G.]]
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[[Category: Sprangers R]]
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[[Category: Mrna processing]]
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[[Category: Stier G]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:45:54 2009''
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Current revision

SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN

PDB ID 1g5v

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