This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1c3b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:38, 13 March 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1c3b.png|left|200px]]
 
-
<!--
+
==AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB)==
-
The line below this paragraph, containing "STRUCTURE_1c3b", creates the "Structure Box" on the page.
+
<StructureSection load='1c3b' size='340' side='right'caption='[[1c3b]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1c3b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C3B FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BZB:BENZO[B]THIOPHENE-2-BORONIC+ACID'>BZB</scene></td></tr>
-
{{STRUCTURE_1c3b| PDB=1c3b | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c3b OCA], [https://pdbe.org/1c3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c3b RCSB], [https://www.ebi.ac.uk/pdbsum/1c3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c3b ProSAT]</span></td></tr>
-
 
+
</table>
-
===AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB)===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_10595535}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 10595535 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/1c3b_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_10595535}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1C3B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3B OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c3b ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
<ref group="xtra">PMID:10595535</ref><references group="xtra"/>
+
</StructureSection>
-
[[Category: Beta-lactamase]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Escherichia coli]]
+
[[Category: Large Structures]]
-
[[Category: Baquero, F.]]
+
[[Category: Baquero F]]
-
[[Category: Blazquez, J.]]
+
[[Category: Blazquez J]]
-
[[Category: Morosini, M I.]]
+
[[Category: Morosini MI]]
-
[[Category: Powers, R A.]]
+
[[Category: Powers RA]]
-
[[Category: Shoichet, B K.]]
+
[[Category: Shoichet BK]]
-
[[Category: Weston, G S.]]
+
[[Category: Weston GS]]
-
[[Category: Beta-lactamase]]
+
-
[[Category: Cephalosporinase]]
+
-
[[Category: Serine hydrolase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:41:46 2009''
+

Current revision

AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR, BENZO(B)THIOPHENE-2-BORONIC ACID (BZB)

PDB ID 1c3b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1c3b"
Personal tools