1f8v

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{{Seed}}
 
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[[Image:1f8v.png|left|200px]]
 
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==THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA==
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The line below this paragraph, containing "STRUCTURE_1f8v", creates the "Structure Box" on the page.
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<StructureSection load='1f8v' size='340' side='right'caption='[[1f8v]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f8v]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Pariacoto_virus Pariacoto virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F8V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1f8v| PDB=1f8v | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f8v OCA], [https://pdbe.org/1f8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f8v RCSB], [https://www.ebi.ac.uk/pdbsum/1f8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f8v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_PAV CAPSD_PAV] Capsid protein alpha self-assembles to form an icosahedral procapsid with a T=3 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins trimers. In addition, calcium ions are incorporated per capsid during assembly. The capsid encapsulates the two genomic RNAs. Capsid maturation occurs via autoproteolytic cleavage of capsid protein alpha generating capsid protein beta and the membrane-active peptide gamma (By similarity). Peptide gamma: membrane-permeabilizing peptide produced by virus maturation, thereby creating the infectious virion. After endocytosis into the host cell, peptide gamma is probably exposed in endosomes, where it permeabilizes the endosomal membrane, facilitating translocation of viral capsid or RNA into the cytoplasm (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f8/1f8v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f8v ConSurf].
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<div style="clear:both"></div>
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===THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA===
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11135676}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11135676 is the PubMed ID number.
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[[Category: Pariacoto virus]]
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[[Category: Ball LA]]
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{{ABSTRACT_PUBMED_11135676}}
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[[Category: Johnson JE]]
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[[Category: Johnson KN]]
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==About this Structure==
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[[Category: Lin T]]
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1F8V is a 7 chains structure of sequences from [http://en.wikipedia.org/wiki/Pariacato_virus Pariacato virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F8V OCA].
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[[Category: Tang L]]
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[[Category: Yeager M]]
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==Reference==
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<ref group="xtra">PMID:11135676</ref><references group="xtra"/>
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[[Category: Pariacato virus]]
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[[Category: Ball, L A.]]
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[[Category: Johnson, J E.]]
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[[Category: Johnson, K N.]]
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[[Category: Lin, T.]]
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[[Category: Tang, L.]]
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[[Category: Yeager, M.]]
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[[Category: Beta-sandwich]]
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[[Category: Coat protein]]
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[[Category: Gamma polypeptide]]
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[[Category: Icosahedral virus]]
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[[Category: Nodavirus]]
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[[Category: Nucleoprotein]]
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[[Category: Protein-rna interaction]]
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[[Category: Rna cage]]
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[[Category: Rna duplex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 08:10:49 2009''
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Current revision

THE STRUCTURE OF PARIACOTO VIRUS REVEALS A DODECAHEDRAL CAGE OF DUPLEX RNA

PDB ID 1f8v

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