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2b97
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2b97" size="450" color="white" frame="true" align="right" spinBox="true" caption="2b97, resolution 0.75Å" /> '''Ultra-high resolutio...) |
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| - | [[Image:2b97.gif|left|200px]]<br /><applet load="2b97" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2b97, resolution 0.75Å" /> | ||
| - | '''Ultra-high resolution structure of hydrophobin HFBII'''<br /> | ||
| - | == | + | ==Ultra-high resolution structure of hydrophobin HFBII== |
| - | Hydrophobins are small proteins secreted by filamentous fungi that have a | + | <StructureSection load='2b97' size='340' side='right'caption='[[2b97]], [[Resolution|resolution]] 0.75Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2b97]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B97 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b97 OCA], [https://pdbe.org/2b97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b97 RCSB], [https://www.ebi.ac.uk/pdbsum/2b97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b97 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HYP2_HYPJE HYP2_HYPJE] Responsible for spore hydrophobicity and protection. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b9/2b97_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b97 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Hydrophobins are small proteins secreted by filamentous fungi that have a unique ability to spontaneously form amphiphilic layers. Hydrophobins have only recently been structurally characterized through the first crystal structure determination of a protein of this class, Trichoderma reesei hydrophobin HFBII [Hakanpaa, Paananen et al. (2004), J. Biol. Chem. 279, 534-539]. The resolution of the HFBII structure has now been extended to an ultrahigh resolution of 0.75 A. The structure was refined conventionally and multipole refinement has been initiated. The ultrahigh-resolution structure is analyzed here in detail and comparison is made to the previous atomic resolution structure of the same protein as well as to other ultrahigh-resolution structures found in the Protein Data Bank. | ||
| - | + | Hydrophobin HFBII in detail: ultrahigh-resolution structure at 0.75 A.,Hakanpaa J, Linder M, Popov A, Schmidt A, Rouvinen J Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):356-67. Epub 2006, Mar 18. PMID:16552136<ref>PMID:16552136</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: | + | <div class="pdbe-citations 2b97" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: Hakanpaa | + | <references/> |
| - | [[Category: Linder | + | __TOC__ |
| - | [[Category: Popov | + | </StructureSection> |
| - | [[Category: Rouvinen | + | [[Category: Large Structures]] |
| - | [[Category: Schmidt | + | [[Category: Trichoderma reesei]] |
| - | + | [[Category: Hakanpaa J]] | |
| - | + | [[Category: Linder M]] | |
| - | + | [[Category: Popov A]] | |
| - | + | [[Category: Rouvinen J]] | |
| - | + | [[Category: Schmidt A]] | |
| - | + | ||
| - | + | ||
Current revision
Ultra-high resolution structure of hydrophobin HFBII
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