2cya
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:2cya.png|left|200px]] | ||
- | + | ==Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix== | |
- | + | <StructureSection load='2cya' size='340' side='right'caption='[[2cya]], [[Resolution|resolution]] 2.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2cya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYA FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cya OCA], [https://pdbe.org/2cya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cya RCSB], [https://www.ebi.ac.uk/pdbsum/2cya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cya ProSAT], [https://www.topsan.org/Proteins/RSGI/2cya TOPSAN]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SYY_AERPE SYY_AERPE] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02009] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cya_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cya ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
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- | < | + | |
[[Category: Aeropyrum pernix]] | [[Category: Aeropyrum pernix]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Bessho | + | [[Category: Bessho Y]] |
- | [[Category: Chen | + | [[Category: Chen L]] |
- | [[Category: Kobayashi | + | [[Category: Kobayashi T]] |
- | [[Category: Kuramitsu | + | [[Category: Kuramitsu S]] |
- | [[Category: Kuratani | + | [[Category: Kuratani M]] |
- | [[Category: Kuroishi | + | [[Category: Kuroishi C]] |
- | [[Category: Liu | + | [[Category: Liu ZJ]] |
- | [[Category: Murayama | + | [[Category: Murayama K]] |
- | + | [[Category: Sakai H]] | |
- | [[Category: Sakai | + | [[Category: Sekine SI]] |
- | [[Category: Sekine | + | [[Category: Shirouzu M]] |
- | [[Category: Shirouzu | + | [[Category: Takahashi M]] |
- | [[Category: Takahashi | + | [[Category: Terada T]] |
- | [[Category: Terada | + | [[Category: Wang BC]] |
- | [[Category: Wang | + | [[Category: Yanagisawa T]] |
- | [[Category: Yanagisawa | + | [[Category: Yokoyama S]] |
- | [[Category: Yokoyama | + | |
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Current revision
Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix
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Categories: Aeropyrum pernix | Large Structures | Bessho Y | Chen L | Kobayashi T | Kuramitsu S | Kuratani M | Kuroishi C | Liu ZJ | Murayama K | Sakai H | Sekine SI | Shirouzu M | Takahashi M | Terada T | Wang BC | Yanagisawa T | Yokoyama S