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2ai9
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2ai9.png|left|200px]] | ||
| - | + | ==S.aureus Polypeptide Deformylase== | |
| - | + | <StructureSection load='2ai9' size='340' side='right'caption='[[2ai9]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2ai9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AI9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ai9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ai9 OCA], [https://pdbe.org/2ai9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ai9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ai9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ai9 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163] | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ai/2ai9_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ai9 ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | == | + | __TOC__ |
| - | < | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Staphylococcus aureus]] | [[Category: Staphylococcus aureus]] | ||
| - | [[Category: Aubart | + | [[Category: Aubart K]] |
| - | [[Category: Christensen | + | [[Category: Christensen SB]] |
| - | [[Category: Fosberry | + | [[Category: Fosberry A]] |
| - | [[Category: Jones | + | [[Category: Jones J]] |
| - | [[Category: Lewis | + | [[Category: Lewis C]] |
| - | [[Category: Lonetto | + | [[Category: Lonetto M]] |
| - | [[Category: McManus | + | [[Category: McManus E]] |
| - | [[Category: Petit | + | [[Category: Petit CM]] |
| - | [[Category: Smith | + | [[Category: Smith KJ]] |
| - | [[Category: Smyth | + | [[Category: Smyth M]] |
| - | + | ||
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| - | + | ||
Current revision
S.aureus Polypeptide Deformylase
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Categories: Large Structures | Staphylococcus aureus | Aubart K | Christensen SB | Fosberry A | Jones J | Lewis C | Lonetto M | McManus E | Petit CM | Smith KJ | Smyth M

