This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1rpi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:24, 14 February 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1rpi.png|left|200px]]
 
-
<!--
+
==Crystal structures of a Multidrug-Resistant HIV-1 Protease Reveal an Expanded Active Site Cavity==
-
The line below this paragraph, containing "STRUCTURE_1rpi", creates the "Structure Box" on the page.
+
<StructureSection load='1rpi' size='340' side='right'caption='[[1rpi]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1rpi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RPI FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
-
{{STRUCTURE_1rpi| PDB=1rpi | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rpi OCA], [https://pdbe.org/1rpi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rpi RCSB], [https://www.ebi.ac.uk/pdbsum/1rpi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rpi ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9QM22_9HIV1 Q9QM22_9HIV1]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rp/1rpi_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rpi ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structures of a Multidrug-Resistant HIV-1 Protease Reveal an Expanded Active Site Cavity===
+
==See Also==
-
 
+
*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_14990731}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 14990731 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_14990731}}
+
-
 
+
-
==About this Structure==
+
-
1RPI is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RPI OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:14990731</ref><references group="xtra"/>
+
-
[[Category: HIV-1 retropepsin]]
+
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
-
[[Category: Koepke, J I.]]
+
[[Category: Large Structures]]
-
[[Category: Kovari, L C.]]
+
[[Category: Koepke JI]]
-
[[Category: Logsdon, B C.]]
+
[[Category: Kovari LC]]
-
[[Category: Martin, P.]]
+
[[Category: Logsdon BC]]
-
[[Category: Merigan, T C.]]
+
[[Category: Martin P]]
-
[[Category: Proteasa, G.]]
+
[[Category: Merigan TC]]
-
[[Category: Terlecky, S R.]]
+
[[Category: Proteasa G]]
-
[[Category: Vickrey, J F.]]
+
[[Category: Terlecky SR]]
-
[[Category: Wawrzak, Z.]]
+
[[Category: Vickrey JF]]
-
[[Category: Winters, M A.]]
+
[[Category: Wawrzak Z]]
-
[[Category: Aid]]
+
[[Category: Winters MA]]
-
[[Category: Aspartyl portease]]
+
-
[[Category: Hiv protease]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Multi-drug resistance]]
+
-
[[Category: Polyprotein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:12:57 2009''
+

Current revision

Crystal structures of a Multidrug-Resistant HIV-1 Protease Reveal an Expanded Active Site Cavity

PDB ID 1rpi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rpi"
Personal tools