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1dfa

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{{Seed}}
 
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[[Image:1dfa.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF PI-SCEI IN C2 SPACE GROUP==
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The line below this paragraph, containing "STRUCTURE_1dfa", creates the "Structure Box" on the page.
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<StructureSection load='1dfa' size='340' side='right'caption='[[1dfa]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1dfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DFA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dfa OCA], [https://pdbe.org/1dfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dfa RCSB], [https://www.ebi.ac.uk/pdbsum/1dfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dfa ProSAT]</span></td></tr>
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{{STRUCTURE_1dfa| PDB=1dfa | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VATA_YEAST VATA_YEAST] Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase (vacuolar ATPase) is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. It is an electrogenic proton pump that generates a proton motive force of 180 mV, inside positive and acidic, in the vacuolar membrane vesicles. It may participate in maintenance of cytoplasmic Ca(2+) homeostasis. This is a catalytic subunit.<ref>PMID:1534148</ref> PI-SceI is an endonuclease that can cleave at a site present in a VMA1 allele that lacks the derived endonuclease segment of the open reading frame; cleavage at this site only occurs during meiosis and initiates "homing", a genetic event that converts a VMA1 allele lacking VDE into one that contains it.<ref>PMID:1534148</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/1dfa_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dfa ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF PI-SCEI IN C2 SPACE GROUP===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10644733}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10644733 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_10644733}}
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==About this Structure==
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1DFA is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DFA OCA].
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==Reference==
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<ref group="xtra">PMID:10644733</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Crist, M.]]
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[[Category: Crist M]]
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[[Category: Duan, X.]]
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[[Category: Duan X]]
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[[Category: Gimble, F S.]]
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[[Category: Gimble FS]]
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[[Category: Hu, D.]]
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[[Category: Hu D]]
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[[Category: Quiocho, F A.]]
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[[Category: Quiocho FA]]
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[[Category: Homing endonuclease]]
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[[Category: Hydrolase]]
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[[Category: Intein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:33:15 2009''
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Current revision

CRYSTAL STRUCTURE OF PI-SCEI IN C2 SPACE GROUP

PDB ID 1dfa

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