2i6w

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{{Seed}}
 
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[[Image:2i6w.png|left|200px]]
 
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==Crystal structure of the multidrug efflux transporter AcrB==
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The line below this paragraph, containing "STRUCTURE_2i6w", creates the "Structure Box" on the page.
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<StructureSection load='2i6w' size='340' side='right'caption='[[2i6w]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2i6w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6W FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6w OCA], [https://pdbe.org/2i6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6w RCSB], [https://www.ebi.ac.uk/pdbsum/2i6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6w ProSAT]</span></td></tr>
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{{STRUCTURE_2i6w| PDB=2i6w | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of the multidrug efflux transporter AcrB===
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[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_17275331}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 17275331 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6w_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_17275331}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6w ConSurf].
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2I6W is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6W OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:17275331</ref><references group="xtra"/>
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__TOC__
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[[Category: Escherichia coli]]
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</StructureSection>
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[[Category: Das, D.]]
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[[Category: Large Structures]]
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[[Category: Kim, S H.]]
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[[Category: Das D]]
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[[Category: Xu, Q S.]]
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[[Category: Kim SH]]
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[[Category: Acrb]]
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[[Category: Xu QS]]
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[[Category: Membrane protein]]
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[[Category: Multidrug efflux transporter]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:17:22 2009''
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Current revision

Crystal structure of the multidrug efflux transporter AcrB

PDB ID 2i6w

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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