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1h5t

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{{Seed}}
 
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[[Image:1h5t.png|left|200px]]
 
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==Thymidylyltransferase complexed with Thymidylyldiphosphate-glucose==
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The line below this paragraph, containing "STRUCTURE_1h5t", creates the "Structure Box" on the page.
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<StructureSection load='1h5t' size='340' side='right'caption='[[1h5t]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1h5t]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H5T FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAU:2DEOXY-THYMIDINE-5-DIPHOSPHO-ALPHA-D-GLUCOSE'>DAU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
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{{STRUCTURE_1h5t| PDB=1h5t | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h5t OCA], [https://pdbe.org/1h5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h5t RCSB], [https://www.ebi.ac.uk/pdbsum/1h5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h5t ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RMLA1_ECOLI RMLA1_ECOLI] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h5/1h5t_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h5t ConSurf].
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<div style="clear:both"></div>
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===THYMIDYLYLTRANSFERASE COMPLEXED WITH THYMIDYLYLDIPHOSPHATE-GLUCOSE===
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==See Also==
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*[[Glucose-1-phosphate thymidylyltransferase 3D structures|Glucose-1-phosphate thymidylyltransferase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_11697907}}, adds the Publication Abstract to the page
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[[Category: Escherichia coli]]
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(as it appears on PubMed at http://www.pubmed.gov), where 11697907 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Bolognesi M]]
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{{ABSTRACT_PUBMED_11697907}}
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[[Category: Rosano C]]
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[[Category: Zuccotti S]]
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==About this Structure==
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1H5T is a 4 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H5T OCA].
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==Reference==
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<ref group="xtra">PMID:11697907</ref><references group="xtra"/>
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[[Category: Glucose-1-phosphate thymidylyltransferase]]
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[[Category: Bolognesi, M.]]
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[[Category: Rosano, C.]]
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[[Category: Zuccotti, S.]]
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[[Category: Nucleotide sugar methabolism]]
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[[Category: Pyrophosphatase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:33:02 2009''
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Current revision

Thymidylyltransferase complexed with Thymidylyldiphosphate-glucose

PDB ID 1h5t

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