2ck5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2ck5" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ck5" /> '''SOLUTION STRUCTURE OF DELTA 1-7 AOSK1'''<br ...)
Current revision (07:49, 23 October 2024) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2ck5.jpg|left|200px]]<br /><applet load="2ck5" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2ck5" />
 
-
'''SOLUTION STRUCTURE OF DELTA 1-7 AOSK1'''<br />
 
-
==About this Structure==
+
==Solution structure of Delta 1-7 aOSK1==
-
2CK5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CK5 OCA].
+
<StructureSection load='2ck5' size='340' side='right'caption='[[2ck5]]' scene=''>
-
[[Category: Single protein]]
+
== Structural highlights ==
-
[[Category: Alphonse, S.]]
+
<table><tr><td colspan='2'>[[2ck5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Orthochirus_scrobiculosus Orthochirus scrobiculosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CK5 FirstGlance]. <br>
-
[[Category: Bernard, C.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-
[[Category: Darbon, H.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ck5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ck5 OCA], [https://pdbe.org/2ck5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ck5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ck5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ck5 ProSAT]</span></td></tr>
-
[[Category: Mouhat, S.]]
+
</table>
-
[[Category: Sabatier, J.M.]]
+
== Function ==
-
[[Category: ion channel blocker]]
+
[https://www.uniprot.org/uniprot/KAX37_ORTSC KAX37_ORTSC] Blocks voltage-gated potassium channels Kv1.1/KCNA1 (IC(50)=0.6nM), Kv1.2/KCNA2 (IC(50)=5.4nM), Kv1.3/KCNA3 (IC(50)=0.014nM) potently, and moderately block intermediate conductance calcium-activated potassium channels KCa3.1/KCNN4 (IC(50)=225nM). At high concentration (2 mM), is also active on Kv1.6/KCNA6 and Shaker IR.[REFERENCE:1]<ref>PMID:15588251</ref>
-
[[Category: ion channel inhibitor]]
+
-
[[Category: ionic channel inhibitor]]
+
-
[[Category: neurotoxin]]
+
-
[[Category: osk1]]
+
-
[[Category: potassium channel inhibitor]]
+
-
[[Category: scorpio toxin]]
+
-
[[Category: toxin]]
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:09:02 2007''
+
==See Also==
 +
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Orthochirus scrobiculosus]]
 +
[[Category: Alphonse S]]
 +
[[Category: Bernard C]]
 +
[[Category: Darbon H]]
 +
[[Category: Mouhat S]]
 +
[[Category: Sabatier JM]]

Current revision

Solution structure of Delta 1-7 aOSK1

PDB ID 2ck5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ck5"
Personal tools