3bfx

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{{Seed}}
 
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[[Image:3bfx.png|left|200px]]
 
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==Crystal structure of human sulfotransferase SULT1C1 in complex with PAP==
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The line below this paragraph, containing "STRUCTURE_3bfx", creates the "Structure Box" on the page.
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<StructureSection load='3bfx' size='340' side='right'caption='[[3bfx]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2etg 2etg] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zhe 1zhe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BFX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene></td></tr>
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{{STRUCTURE_3bfx| PDB=3bfx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bfx OCA], [https://pdbe.org/3bfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bfx RCSB], [https://www.ebi.ac.uk/pdbsum/3bfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bfx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ST1C2_HUMAN ST1C2_HUMAN] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bf/3bfx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bfx ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of human sulfotransferase SULT1C1 in complex with PAP===
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==See Also==
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*[[Sulfotransferase 3D structures|Sulfotransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3BFX is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1zhe 1zhe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BFX OCA].
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==Reference==
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<ref group="xtra">PMID:16804942</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Dombrovski, L.]]
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[[Category: Bochkarev A]]
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[[Category: Dong, A.]]
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[[Category: Dombrovski L]]
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[[Category: Edwards, A M.]]
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[[Category: Dong A]]
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[[Category: Loppnau, P.]]
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[[Category: Edwards AM]]
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[[Category: Plotnikov, A N.]]
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[[Category: Loppnau P]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Plotnikov AN]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom M]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Alternative splicing]]
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[[Category: Cytoplasm]]
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[[Category: Pap]]
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[[Category: Polymorphism]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Sulfotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:46:11 2009''
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Current revision

Crystal structure of human sulfotransferase SULT1C1 in complex with PAP

PDB ID 3bfx

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