This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1fsy

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:16, 27 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1fsy.png|left|200px]]
 
-
<!--
+
==AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID==
-
The line below this paragraph, containing "STRUCTURE_1fsy", creates the "Structure Box" on the page.
+
<StructureSection load='1fsy' size='340' side='right'caption='[[1fsy]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1fsy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FSY FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=105:N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC+ACID+AMIDE]+BORONIC+ACID'>105</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
{{STRUCTURE_1fsy| PDB=1fsy | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fsy OCA], [https://pdbe.org/1fsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fsy RCSB], [https://www.ebi.ac.uk/pdbsum/1fsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fsy ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fs/1fsy_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fsy ConSurf].
 +
<div style="clear:both"></div>
-
===AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID===
+
==See Also==
-
 
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_11182316}}, adds the Publication Abstract to the page
+
[[Category: Escherichia coli K-12]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 11182316 is the PubMed ID number.
+
[[Category: Large Structures]]
-
-->
+
[[Category: Blasczcak LC]]
-
{{ABSTRACT_PUBMED_11182316}}
+
[[Category: Caselli E]]
-
 
+
[[Category: Powers RA]]
-
==About this Structure==
+
[[Category: Prati F]]
-
1FSY is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FSY OCA].
+
[[Category: Shoichet BK]]
-
 
+
[[Category: Wu CY]]
-
==Reference==
+
-
<ref group="xtra">PMID:11182316</ref><references group="xtra"/>
+
-
[[Category: Beta-lactamase]]
+
-
[[Category: Escherichia coli]]
+
-
[[Category: Blasczcak, L C.]]
+
-
[[Category: Caselli, E.]]
+
-
[[Category: Powers, R A.]]
+
-
[[Category: Prati, F.]]
+
-
[[Category: Shoichet, B K.]]
+
-
[[Category: Wu, C Y.]]
+
-
[[Category: Beta-lactamase]]
+
-
[[Category: Cephalosporinase]]
+
-
[[Category: Serine hydrolase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:46:34 2009''
+

Current revision

AMPC BETA-LACTAMASE FROM E. COLI COMPLEXED WITH INHIBITOR CLOXACILLINBORONIC ACID

PDB ID 1fsy

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fsy"
Personal tools