This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ig3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:35, 7 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ig3.png|left|200px]]
 
-
<!--
+
==Mouse Thiamin Pyrophosphokinase Complexed with Thiamin==
-
The line below this paragraph, containing "STRUCTURE_1ig3", creates the "Structure Box" on the page.
+
<StructureSection load='1ig3' size='340' side='right'caption='[[1ig3]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ig3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IG3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IG3 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VIB:3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM'>VIB</scene></td></tr>
-
{{STRUCTURE_1ig3| PDB=1ig3 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ig3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ig3 OCA], [https://pdbe.org/1ig3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ig3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ig3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ig3 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Mouse Thiamin Pyrophosphokinase Complexed with Thiamin===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/TPK1_MOUSE TPK1_MOUSE] Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.<ref>PMID:10567383</ref> <ref>PMID:16365036</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_11419946}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 11419946 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ig/1ig3_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_11419946}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1IG3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IG3 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ig3 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:11419946</ref><references group="xtra"/>
+
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Thiamine diphosphokinase]]
+
[[Category: Baker L-J]]
-
[[Category: Baker, L J.]]
+
[[Category: Harris RA]]
-
[[Category: Harris, R A.]]
+
[[Category: Liu J]]
-
[[Category: Liu, J.]]
+
[[Category: Timm DE]]
-
[[Category: Timm, D E.]]
+
-
[[Category: Alpha/beta/alpha sandwich]]
+
-
[[Category: Beta barrel]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:49:51 2009''
+

Current revision

Mouse Thiamin Pyrophosphokinase Complexed with Thiamin

PDB ID 1ig3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ig3"
Personal tools