This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2crg
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2crg" size="450" color="white" frame="true" align="right" spinBox="true" caption="2crg" /> '''Solution structure of the myb-like DNA-bindi...) |
|||
| (15 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2crg.gif|left|200px]]<br /><applet load="2crg" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2crg" /> | ||
| - | '''Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein'''<br /> | ||
| - | == | + | ==Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein== |
| - | + | <StructureSection load='2crg' size='340' side='right'caption='[[2crg]]' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2crg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2crg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2crg OCA], [https://pdbe.org/2crg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2crg RCSB], [https://www.ebi.ac.uk/pdbsum/2crg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2crg ProSAT], [https://www.topsan.org/Proteins/RSGI/2crg TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTA3_MOUSE MTA3_MOUSE] Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/2crg_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2crg ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Endo H]] | |
| - | [[Category: Endo | + | [[Category: Hayashi F]] |
| - | [[Category: Hayashi | + | [[Category: Yokoyama S]] |
| - | + | [[Category: Yoshida M]] | |
| - | [[Category: Yokoyama | + | |
| - | [[Category: Yoshida | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the myb-like DNA-binding domain of mouse MTA3 protein
| |||||||||||
