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3baf

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{{Seed}}
 
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[[Image:3baf.png|left|200px]]
 
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<!--
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==Crystal structure of shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP==
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The line below this paragraph, containing "STRUCTURE_3baf", creates the "Structure Box" on the page.
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<StructureSection load='3baf' size='340' side='right'caption='[[3baf]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3baf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BAF FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
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{{STRUCTURE_3baf| PDB=3baf | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3baf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3baf OCA], [https://pdbe.org/3baf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3baf RCSB], [https://www.ebi.ac.uk/pdbsum/3baf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3baf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROK_MYCTU AROK_MYCTU] Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<ref>PMID:11483005</ref> <ref>PMID:17020768</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3baf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3baf ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP===
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==See Also==
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*[[Shikimate kinase 3D structures|Shikimate kinase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3BAF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAF OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Shikimate kinase]]
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[[Category: Azevedo WF]]
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[[Category: Azevedo, W F.]]
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[[Category: Basso LA]]
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[[Category: Basso, L A.]]
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[[Category: Dias MVB]]
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[[Category: Dias, M V.B.]]
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[[Category: Faim LM]]
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[[Category: Faim, L M.]]
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[[Category: Ruggiero NJ]]
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[[Category: Ruggiero, N J.]]
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[[Category: Santos DS]]
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[[Category: Santos, D S.]]
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[[Category: Vasconcelos IG]]
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[[Category: Vasconcelos, I G.]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Amp-pnp]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: Shikimate kinase]]
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[[Category: Shikimate pathway]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:16:31 2009''
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Current revision

Crystal structure of shikimate kinase from Mycobacterium tuberculosis in complex with AMP-PNP

PDB ID 3baf

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