2cuf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2cuf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cuf" /> '''Solution structure of the homeobox domain of...)
Current revision (11:31, 22 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2cuf.gif|left|200px]]<br /><applet load="2cuf" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2cuf" />
 
-
'''Solution structure of the homeobox domain of the human hypothetical protein FLJ21616'''<br />
 
-
==About this Structure==
+
==Solution structure of the homeobox domain of the human hypothetical protein FLJ21616==
-
2CUF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CUF OCA].
+
<StructureSection load='2cuf' size='340' side='right'caption='[[2cuf]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2cuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUF FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cuf OCA], [https://pdbe.org/2cuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cuf RCSB], [https://www.ebi.ac.uk/pdbsum/2cuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cuf ProSAT], [https://www.topsan.org/Proteins/RSGI/2cuf TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HMBX1_HUMAN HMBX1_HUMAN] Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor.<ref>PMID:16825764</ref> <ref>PMID:19757162</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/2cuf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cuf ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Inoue, M.]]
+
[[Category: Inoue M]]
-
[[Category: Kigawa, T.]]
+
[[Category: Kigawa T]]
-
[[Category: Koshiba, S.]]
+
[[Category: Koshiba S]]
-
[[Category: Ohnishi, S.]]
+
[[Category: Ohnishi S]]
-
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+
[[Category: Tomizawa T]]
-
[[Category: Tomizawa, T.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S.]]
+
-
[[Category: flj21616]]
+
-
[[Category: hepatocyte transcription factor]]
+
-
[[Category: homeobox domain]]
+
-
[[Category: loop insertion]]
+
-
[[Category: national project on protein structural and functional analyses]]
+
-
[[Category: nppsfa]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomics]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:16:14 2007''
+

Current revision

Solution structure of the homeobox domain of the human hypothetical protein FLJ21616

PDB ID 2cuf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cuf"
Personal tools